Ch'rell is a dangerous enemy of the Utroms; as it would happen, he was being transported as their prisoner but escaped and sabotaged their spacecraft. The Utrom crash-landed on Earth during the Sengoku period of feudal Japanese history, forced into hiding using their exo-suits. Ch'rell confiscated one such suit and used the legend of the demon Shredder to craft a dual identity, becoming Oroku Saki and the new Shredder. He also founded the Foot
Clan, which grew into a massive underground criminal empire by the 20th century. In the late 20th century, he discovers an abandoned girl named Karai, whom he adopted and trained. Outside of the Utroms, she is the only one initially to know the truth about him. Despite not being the demonic version of the Shredder, Ch'rell is shown to have contacts with the mystical world, visible by the fact that some of his minions are supernatural beings. Throughout it all, Shredder hunts for the Utroms to exact his revenge and prevent them from re-capturing him.
While in New York City to establish a branch of the clan there, Shredder locates Hamato Yoshi, one of the Utroms' foremost guardians, and kills him after failing to force their location from him. During the struggle, Yoshi's pet rat, Splinter, escapes and winds up in the city's sewers where he and four baby turtles are accidentally exposed to mutagenic ooze created by the Utroms and consequently mutate into sentient humanoid forms.
Fifteen years later, the Turtles begin encountering the Foot Clan and unknowingly foil several of Shredder's plans. Shredder reveals himself to the Turtles and (after failing to make them ally with him) becomes their bitter enemy. He loses his first major battle against them and Splinter, but he later deals them a crushing defeat, in which Leonardo is severely beaten, April O'Neil's antique shop is burned to the ground and everyone is presumed dead. After recovering out of town, Leonardo leads his brothers and Splinter in an attack on Foot headquarters, culminating in Shredder's beheading. Not knowing his Utrom nature, the Turtles think him dead.
However, Ch'rell survived, but was gravely injured. As his body was healed, Karai assumed leadership of the Foot Clan, ending an ensuing war for control of New York City and supposedly making peace with the Turtles. But when Ch'rell returned, he vowed to destroy the Turtles by any means necessary. After the Turtles help repel a Triceraton invasion, New York City is heavily damaged. Oroku Saki steps forward to help rebuild, spending millions as a cover to retrieve Triceraton technology that was left behind. He has a spacecraft constructed, so that he may leave before the Utroms return for him. It is completed, but his plan suffers complications courtesy of the Turtles, their allies and Agent Bishop. The ship is launched, but the Turtles and Splinter sneak aboard. In a more powerful exo-suit, he easily defeats them. The Turtles and Splinter self-destruct the ship to stop the Shredder, but the timely arrival of the Utroms saves all their lives. On the Utrom homeworld, Ch'rell is placed on trial, found guilty and sentenced to eternal exile on an icy asteroid.
- The Shredder will become Jeffrey and Jaden's enemy in Jeffrey, Jaden & Friends' Storm Adventures of Teenage Mutant Ninja Turtles.
- The Shredder will become Arik's enemy in Arik's Adventures of Turtles Forever.
- The Shredder is a member of the Horde of Darkness.