The Queen of Hearts (1951 version: currently voiced by Tress MacNeille. 2010 version: portrayed by Helena Bonham Carter) is the main antagonist of Jaden's Adventures of Alice in Wonderland (1951 version). She rules Wonderland with an iron fist, and is very temperamental. If anything doesn't go her way, or angers her, she yells "Off with his/her/their head/s!" to whomever is responsible. She was so determined to have Alice, Jaden and his friends' heads removed (after an incident when playing a game of croquet), but they escaped her.
In Jaden's Adventures of Alice in Wonderland (2010 version), she does worse things to the inhabitants of Wonderland, and they are afraid to face her because she controls a powerful creature called the Jabberwocky. The inhabitants needed Alice's help in order to bring down the "Bloody Big Head's" power. In the end, Alice slays the Jabberwocky, and the White Queen (The Queen of Hearts' sister) regains control of Wonderland, and banishes the The Queen of Hearts.
- The Queen of Hearts will become Jeffrey's enemy in Jeffrey & Friends' Adventures with Alice in Wonderland.
- The Queen of Hearts will return in Jeffrey, Jaden & Friends' Storm Adventures of Disney Villain's Revenge.
- The Red Queen will appear again in Jeffrey, Jaden & Friends' Storm Adventures of Alice Through the Looking Glass.
- Bugs and Daffy will meet the 1951 Queen of Hearts in Bugs and Daffy's Adventures of Alice in Wonderland. Bugs openly sasses her and is almost given the ax.