This is a list of villain on the Jaden's Adventures series and Jeffrey and Friends adventures series:
- Set the God of Chaos
- Nephthys the Goddess of Lamentation
- Anubis the God of Death
- The Chameleon
- Turbo
- Master Xehanort
- Vanitas
- Ansem the Seeker of Darkness
- Xemnas
- Xigbar
- Saïx
- Jafar
- Maleficent
- Myotismon
- Zira
- Forte
- Ursula the Sea Witch
- Doomsday
- Jabba the Hutt
- Nigel (Rio)
- Grundel Toad
- Captain Gutt
- Professor Zundapp
- Pete
- Cruella DeVil
- Plankton
- Hades
- Dr. Facilier
- Judge Claude Frollo
- Diabolico
- Bowser
- Dr. Eggman
- Scar
- Chernabog
- Shan-Yu
- Evil Queen
- Clayton
- Mother Gothel
- Malefor
- Diesel 10
- Devious Diesel
- Discord (Later reforms)
- Queen Chrysalis
- King Sombra
- Queen La
- Ronno
- Diamond Tiara
- Silver Spoon
- Joe the Fish
- Joker
- Lex Luthor
- Steele
- Mildew
- Alvin the Treacherous
- Dagur The Deranged
- The Swarm Lord
- Rasputin
- Prince Froglip
- Rothbart
- Lord Shen
- Tai Lung
- The MCP
- SARK
- Lord Farquaad
- Ashcan & Pete
- Toon Patrol
- Piedmon
- Puppetmon
- Machinedramon
- MetalSeadramon
- Akihiro Kurata
- Belphemon
- Supreme King
- Percival McLeach and Joanna
- Madame Medusa, Mr. Snoops, and Brutus and Nero
- Arthur and Cecil
- Madame Gasket
- Pitch (The Boogeyman)
- Brron, Mad King of Dark World
- Quasimodo Wilson
- Professor Screweyes
- Cleo
- Jessica
- Amazonia
- Lola
- Adolf Hitler
- Mola Ram
- Bowser Jr.
- Mistress 9
- Ranamon
- Shredder
- Dr. Baxter Stockman
- Hun
- The Psycho Rangers
- Slade
- Grandfather (KND)
- Queen Nehelenia
- Team Galactic (Saturn, Mars and Jupiter)
- Master Hand and Crazy Hand
- Morgana the Sea Witch
- Marina Del Rey
- Sa'Luk
- The Metarex
- Aku
- Katz
- Dr. Drakken
- Shego
- Megatron
- Andross
- The Cavity Goon
- Gilda
- Trixie
- Metal Sonic
- Lord Zedd
- Ivan Ooze
- Rita Repulsa
- Goldar
- Admiral Malkor
- Tabuu
- Sunset Shimmer
- The Biskit Twins
- The Ancient Minster
- Loki (Marvel)
- Ridley
- Vilgax
- Frost
- Thunder
- T-Bone
- Blaze
- Cheetato and Cheetata
- Mirage
- Arukenimon
- Mummymon
- Charles Muntz
- Rumpelstiltskin
- El Macho
- Hans
- Duke of Weselton
- Tirek
- Drago Bludvist
- Kylo Ren
- Supreme Leader Snoke
- Yellow Diamond